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Design and Development of Tangentital Spray Rotogranulation Mechanism


Author(s):

Ajinkya Pawar , VIT PUNE; Dr.S.R.Bahulikar, VIT PUNE

Keywords:

Coating, Particle, tangential spray, rotor granulation, validate, spheronization, yielding

Abstract:

Particle of different size is used in various applications in areas like pharmaceutical, agriculture, chemical industry etc. The production of pellets in the pharmaceutical industry generally involves multi-step processing: (1) mixing, (2) wet granulation, (3) spheronization and (4) drying. Fluid-bed rotogranulation (FBRG) is now being considered as an alternative, since it offers the advantages of combining the different steps into one processing unit, thus reducing processing time and material handling. This work aimed at the design and development of a FBRG process for the production of pellets in a GPCG ACG125 tangential spray rotoprocessor and Validation for yielding.


Other Details:

Manuscript Id :IJSTEV2I10288
Published in :Volume : 2, Issue : 10
Publication Date: 01/05/2016
Page(s): 1036-1041
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